Conference Program
Outline of Program Schedule for 2007 Conference
Program current as of September 14th 2007 (may be subject to minor change).
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Sunday 21 October
| 12:00PM - 5:00PM | Conference Registration |
| 5:00PM - 6:00PM | Opening Session
Chair: Ian Smith & John Wade |
| Brian Chait: Proteomic Approaches for Analyzing Complex Biological Machines abs#001 | |
| 6:00PM - 7:00PM | Welcome Reception |
Monday 22 October
| 7:00AM - 8:30AM | Poster Preview |
| Delegates are welcome to browse through the trade hall to observe the posters. | |
| 8:30AM - 10:25AM | Protein Misfolding & Disease
Chair: Kevin Barnham & Yoshiaki Kiso |
| Colin Masters: Alzheimer's disease: Aβ-amyloid as the principal molecular and therapeutic diagnostic target. abs#002 | |
| Jeffery Kelly: Hydrogen Bonding and Hydrophobic Effect Thermodynamic Linkage Creates Protein Folding Hotspots abs#003 | |
| Sheena Radford: Exploring Protein Folding Landscapes: from Ensembles to Single Molecule Methods abs#004 | |
| Stephen Bottomley: The Mechanism of Polyglutamine Protein Aggregation - A story with a twist in its tail. abs#005 | |
| 10:30AM - 11:00AM | Morning Tea |
| 11:00AM - 1:00PM | Peptidomimetics & Drug Design
Chair: Patrick Perlmutter & Dirk Tourwe |
| Garland Marshall: Peptidomimetics of Helical Protein Surfaces: The Devil's in the Details abs#006 | |
| Peter Gluckman: TBA abs#007 | |
| Dawei Ma: Studies on the Smac mimetics and SARS 3CL protease inhibitors abs#009 | |
| William Lubell: Aza-Amino Acid Scanning To Explore Conformation-Biological Activity Relationships abs#008 | |
| 1:00PM - 3:30PM | Poster Session A & Lunch |
| Naoko Abe: O-Acyl isopeptide method for peptide synthesis: Application of O-acyl isodipeptide units to the synthesis of bioactive peptides abs#101 | |
| Marina Ali: Direct labeling of bioactive molecules with technetium to evaluate their biodistribution in arthritic joints by imaging abs#102 | |
| Dominique Bagnard: Peptidic inhibition of the transmembrane domain of Neuropilin-1 inhibits glioma growth in vivo abs#103 | |
| Paul Barrett: The Measurement of Structural Aspects of Melittin and Prion Peptide Interactions with Characterised Supported Lipid Bilayers. abs#104 | |
| Sharon Bishop-Hurley: Combinatorially selected phage-displayed peptides for the control of Campylobacter jejuni in chickens abs#105 | |
| Carine Bourguet: Exploring the relationship between turn geometry and allosteric antagonism of peptide mimic ligands for a prostaglandin receptor abs#106 | |
| Gregory Bourne: Peptidomimetics of helical protein surfaces targeting the E. coli CheY response regulator. abs#107 | |
| Jens Buchardt: Transglutaminase mediated selective PEGylation of human growth hormone abs#108 | |
| Yan Chen: Effect of formulation factors on incorporation of the hydrophilic peptide dalargin into PLGA and mPEG-PLGA nanoparticles abs#109 | |
| Daniel Coles: The Characterisation of Novel Dendritic Carriers with DNA by Isothermal Titration Calorimetry abs#110 | |
| Norelle Daly: Sunflower trypsin inhibitor: A unique scaffold in drug design abs#111 | |
| Aline Dantas de Araujo: Directed Folding of Toxins Using Selenocysteine abs#112 | |
| Yoshio Doi: Incorporation of large nonnatural amino acids into protein by translation with EF-Tu mutants abs#113 | |
| Ann Du: Ligand-Supported Purification of the Urotensin-II Receptor: Towards a General Method for GPCR Purification abs#114 | |
| Samir EL Andaloussi: Applications of cell-penetrating peptides in gene regulation abs#115 | |
| Alysha Elliott: Evolution & insecticidal activity of circular peptides abs#116 | |
| Christian Feckler: Efficient fractionation of mitochondria and plasma-membrane proteins abs#117 | |
| Jordan Fletcher: Microwave-assisted synthesis & biological characterisation of T-cell determinants bearing N-Methylated amides abs#118 | |
| Shi Fu: A novel preparation for inositol trisphosphates abs#119 | |
| Ian Gibbins: Peptides increase neuronal excitability via convergent G-protein coupled receptor signalling pathways that inhibit potassium channels abs#120 | |
| Jean-Francois Hernandez: Solid phase synthesis of dipeptides and dipeptidomimetics substrate-based NOS inhibitors through a side-chain anchoring approach abs#121 | |
| Jan Hlavácek: Oostatic peptides in the flesh fly Neobellieria bullata: Synthesis, distribution and degradation abs#122 | |
| Ralf Hoffmann: Mapping of phosphorylation dependent monoclonal antibodies in immunoblots using human tau-constructs synthesized by native chemical ligation abs#123 | |
| John Huynh: Is helix VIII of G protein-coupled receptors a lipid-activated signalling sensor? abs#124 | |
| Reito Ikeda: Loss of Sweetness of Monatin with Lactamization abs#125 | |
| Nui Ito: A novel application of the isopeptide method to synthesize difficult sequence-containing peptide abs#126 | |
| Yuji Ito: Binding peptides specific to low pH-induced conformer of human IgG-Fc: application for conformational analysis and affinity purification abs#127 | |
| Henrik Johansson: Characterization of a novel cytotoxic cell-penetrating peptide derived from p14ARF protein abs#128 | |
| Bishnu Joshi: Design and Synthesis of New Peptide Sensor for Detection of Zn2+ based on Modular Approach abs#129 | |
| John Juliano: Back to BACE-ics - Peptidomimetic inhibitor design, assaying strategies & expression of β-Secretase abs#130 | |
| JiEun Jung: Polyubiquitin conjugates with lysine-specific linkage: Synthesis and structural characterization using high resolution mass spectrometry abs#131 | |
| Hirochika Kawakami: Efficient solid-phase synthesis of labeled β-structured peptides used for peptide arrays abs#132 | |
| Sung Kim: Synthesis of pseudopeptides containing reduced amide bonds corresponding to indolicidin and their biological activities abs#133 | |
| Chuang Fong Kong: Robust enrichment of phosphpeptides from serum using titania coated magnetic beads for rapid profiling of biomarkers by mass spectrometry abs#134 | |
| Tzong-Hsien (John) Lee: Reversed Phase and Immobilised Phospholipid Chromatographic Separation of Mouse Liver Microsomal Proteins for Membrane Proteome Analysis abs#135 | |
| Joohee Lee: γ3 -PNA : RNA Specific Binding Peptide Nucleic Acid abs#136 | |
| Jisoo Lim: 14-Helical β3-Peptide Stabilized by Cation-π Interaction abs#137 | |
| Lihong Liu: Cholesterol-Terminated PEG-TAT Micelle as Novel Carrier for Ciprofloxacin Delivery Targeted to Blood-Brain Barrier abs#138 | |
| Maria Luisa Mangoni: LPS (Endotoxin) is a Key Molecule in the Synergistic Effect of Temporins on Gram-Negative Bacteria abs#139 | |
| Lisandra (Lisa) Martin: Specific and selective peptide-membrane interactions revealed by QCM & AFM abs#140 | |
| Danny Mok: Targeting both intracellular and extracellular protein interactions with Phylomer® peptides abs#141 | |
| Bethny Morrissey: Diving into Domains - Antigenic Peptide Identification using a Mass Spectrometry Based Immunoassay abs#142 | |
| Markus Muttenthaler: Directed folding of α-Conotoxins using selenocysteine abs#143 | |
| Natalia Nalivaeva: Study of the effects of regulatory peptides on expression of amyloid-degrading enzymes abs#144 | |
| Jin-Mi Noh: Kojic acid-Tripeptide Amides and Ascorbic acid-Tripeptide Amides as a New Tyrosinase Inhibitor abs#145 | |
| Yasuhiko Ohtsuka: Synthesis of HC-toxin Hydroxamic Acid Analogs and Their Inhibitory Activity toward Histone Deacetylases abs#146 | |
| Akira Otaka: Development of amino acid derivative with amide cleavage ability and its use for the design of shuttle peptides abs#147 | |
| Yoonkyung Park: Antimicrobial mechanism of an antimicrobial peptide, Pseudin-2, derived from the skin of the paradoxical frog in various membrane lipid compositions abs#148 | |
| Leonard Pattenden: Activation of the Angiotensin I G Protein-Coupled Receptor Involves the Plasma Membrane and Calmodulin as an Early Event of Signal Transduction. abs#149 | |
| Julian Phillips: High-Throughput, Highly Sensitive and Selective Targeted Quantitative Protein Analysis Using High Resolution Selected Reaction Monitoring Assays on a Triple Quadrupole Mass Spectrometer abs#150 | |
| Michael Przybylski: CREDEX-MS: Molecular determination of carbohydrate recognition structures in proteins by proteolytic excision- mass spectrometry abs#151 | |
| Peter Quaedflieg: The use of Peptide Deformylase in industrial peptide synthesis abs#152 | |
| Helena Safavi-Hemami: Profiling and Functional Studies of Venom Isolated from Conus novaehollandiae abs#153 | |
| Christina Schroeder: Structure and activity of neuronally selective mu-conotoxins from Conus striatus abs#154 | |
| Jimmy Sejberg: Bicyclic acidic amino acids as mimetics of Glu or Asp abs#155 | |
| Edith Staes: Does the acylation influence the interaction of ghrelin with lipid membranes? abs#156 | |
| David Steer: Comparison of CID and ETD in the sequencing and identification of Neuropeptides. abs#157 | |
| Vommina Sureshbabu: Total synthesis of Cyclosporin-O abs#158 | |
| Vommina Sureshbabu: Synthesis of tetrazole analogues of amino acids: The Fmoc approach abs#159 | |
| Johan Svenson: Insights into the Protein Binding of Short Cationic Antimicrobial Peptides abs#160 | |
| Hirokazu Tamamura: Identification of Sequential Motifs Relevant to Inhibitory Activity against HIV Integrase abs#161 | |
| Masakazu Tanaka: Molecular design for chiral cyclic α,α -disubstituted amino acids and conformational study of their peptides abs#162 | |
| Dirk Tourwe: Conformational constraints provide new, potent and selective Angiotensin-IV analogs. abs#163 | |
| Nicole van der Weerden: Understanding the Mechanism of Action of a Floral Defensin abs#164 | |
| Jackie Wilce: The Intracellular and Nuclear-targeted Delivery of an Anti-androgen Drug by Carrier Peptides. abs#165 | |
| Nicholas Williamson: Assessing the Proportion and Diversity of Post-Translationally Modified Peptides in the Immunopeptidome abs#166 | |
| Yao-Wen Wu: Quantitative Analysis of the Interaction of Prenylated Rab GTPase with REP and GDI Using Semi-synthetic Fluorescent Sensor abs#167 | |
| Miyuki Yamaguchi: Direct detection of non-covalent complexes of oligo(tyrosine sulfate)s with synthetic heparin-binding peptides by MALDI-TOF-MS abs#168 | |
| Yuanzhong Yang: Field-amplified sample injection: A new high sensitivity method for the analysis of peptides by capillary electrophoresis - mass spectrometry abs#169 | |
| Shee Yong: Improving mass spectrometry analysis in proteomics - Peptide derivatization stratagies abs#170 | |
| Lunch for all delegates will be served at the same time in the trade area. | |
| 3:30PM - 5:30PM | New Developments in Peptide Drug Delivery
Chair: Istvan Toth and Hisakazu Mihara |
| Vladimir Torchilin: Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery abs#010 | |
| Pavla Simerska: Liposaccharides in Peptide Vaccine Delivery abs#011 | |
| Kathryn Woodburn: Hematide™ is Immunologically Distinct from Erythropoietin and Corrects Anemia in a Rat Pure Red Cell Aplasia Model abs#012 | |
| Yoram Schecter: New Technologies to Prolong Life-Time of Peptide and Protein Drugs In vivo abs#013 | |
| William Banks: Delivery of Peptides to the Brain: Emphasis on Therapeutic Development abs#014 | |
| 3:30PM - 5:30PM | Chemical Peptide Synthesis: Innovations & Applications
Chair: John Wade and Saburo Aimoto |
| Yuji Nishiuchi: Chloroform-Phenol Mixed Solvent Essential for Segment Condensation Reaction Performed in Solution or on a Solid Support abs#015 | |
| Andrea Robinson: Applying homogeneous catalysis to the synthesis of peptides abs#016 | |
| Jonathan Collins: New Developments in Microwave Assisted Solid Phase Peptide Synthesis abs#017 | |
| Yoon-Sik Lee: Ladder-Type One-Bead One-Compound (OBOC) Peptide Library on HiCore Resin for the Screening of Kinase Substrates abs#018 | |
| James Tam: Quaternary Protein Mimetic abs#019 | |
| 3:30PM - 5:30PM | Peptidomics: Towards Therapeutics
Chair: Tony Purcell and Malcolm Buckle |
| William Hildebrand: Peptide Epitopes that Distinguish Virus-Infected and Cancerous Cells abs#020 | |
| Matthias Pelzing: Sequence Characterization of Intact Proteins by Consecutive Ion/Ion Reactions of ETD and PTR abs#021 | |
| Michael Przybylski: New molecular approaches for immuno-therapy and -diagnosis of alzhemer's disease based on epitope-specific serum anti-βamyloid autoantibodies abs#022 | |
| Hong Gi Kim: Peptidomic Analysis of Rat Brain Exposed to Cold and Restraint Stress: Identification of a Novel Neuropeptide Derived from Microtubule-associated Protein 2 abs#023 | |
| Christie Hunter: Novel Strategy Involving Peptide MRM-based Assays and Chemistry for Targeted Quantitation of Biomarkers in Plasma abs#024 | |
| 5:30PM - 6:30PM | Happy Hour, Trade & Posters |
Tuesday 23 October
| 7:00AM - 8:30AM | Poster Preview |
| Delegates are welcome to browse through the trade hall to observe the posters. | |
| 8:30AM - 10:30AM | Peptides-to-Clinic
Chair: Richard Houghten and Geoff Frances |
| Pierre De Meyts: Structure, function and evolution of ligands and receptors of the insulin peptide family abs#025 | |
| Anna Papini: An innovative "chemical reverse approach" for autoimmune diseases diagnosis: a consistent strategy to include aberrant post-translational modifications abs#026 | |
| Les Miranda: Design, Synthesis, and Biological Activity of GLP-1 Peptide Agonists abs#027 | |
| Anthony Turner: Evolution of angiotensin converting enzymes and implications for vasoactive peptide metabolism abs#028 | |
| Waleed Danho: Opportunities and Challenges of Developing Peptide Drugs in the Pharmaceutical Industry abs#029 | |
| 10:30AM - 11:00AM | Morning Tea |
| 11:00AM - 1:00PM | Clinical Proteomics
Chair: Ian Smith and Dick Wettenhall |
| Ralph Bradshaw: Post-Translational modifications: Identifying the wheat and sorting the chaff abs#030 | |
| William Hancock: The Challenge of Deep Analysis of the Plasma Proteome for Clinical Proteomics abs#031 | |
| Ed Nice: Faecal Proteomics abs#032 | |
| James Landridge: What can peptide shape tell us? The application of ion mobility coupled with time-of -flight mass spectrometry for detailed peptide structural studies abs#033 | |
| Alan Sawyer: The Monash Antibody Technologies Facility: A high throughput monoclonal antibody production platform for phospho-kinomics and a custom service for Australian and international scientists and companies abs#034 | |
| 1:00PM - 3:30PM | Poster Session B & Lunch |
| Tomoyasu AIZAWA: A novel expression system for recombinant peptide as inclusion body abs#201 | |
| Kalyana Bharati Akondi: Synthesis and characterisation of novel alpha-conotoxin, LeD2 abs#202 | |
| Asif Alam: Rapid identification of protein variants with mass spectrometry abs#203 | |
| Syahir Amir: Highly sensitive anomalous relfection of gold applicable for protein detection abs#204 | |
| Marielle Anger-Leroy: Open Platform for Real-Time Biomolecular Interactions in Array Format without Labelling abs#205 | |
| Martina Baumann: Understanding self-assembled amphiphilic peptide supramolecular structures from primary sequence helix propensity. abs#206 | |
| Heather Benson: Formulation development of chitosan-based nanoparticles for delivery of a hydrophilic hexapeptide abs#207 | |
| Scott Bringans: Proteomic Analysis of the Venom of Heterometrus longimanus (Asian Black Scorpion) abs#208 | |
| Malcolm Buckle: Surface Plasmon Resonance Imagery (SPRi) and the development of novel General Liquid Interface Specific Surfaces (GLISS) for peptide biochips abs#209 | |
| Yoshiro Chuman: Identification of Alternative Splicing Variants of PPM1 Protein Phosphatase PPM1D abs#210 | |
| Cecile Cros: Intranasal delivery of disaccharide modified CNS active peptides abs#211 | |
| André de Roos: Proteolytically derived Bio-active peptides in food applications abs#212 | |
| Nicholas Ede: Mining for Treasures: Systematic Profiling of 8-, 9-, 10-, and 11-mer HLA-B*0702-restricted CD8+ T cell epitopes from the Influenza A/Puerto Rico/8/34 (H1N1) Virus Hemagglutinin with Potential Application in Vaccine Development abs#213 | |
| Ronald Frank: High-density cellulose-bound peptide arrays for systematic studies of peptide-protein interactions abs#214 | |
| Christian Gruber: Enzymatic folding of cystine knot defence peptides abs#215 | |
| Achiel Haemers: Irreversible uPA inhibitors with potent anti-metastatic properties abs#216 | |
| Xiang Han: Synthesis of RGD Mimetic Peptides with Heterocyclic Residues abs#217 | |
| Tom Hennessy: Profiling embryonic developmental stages of zebrafish (danio rerio) abs#218 | |
| Yuji Hidaka: Recognition of the N-Terminal Histone H2A and H3 Peptides by Peptidylarginine Deiminase V abs#219 | |
| Robert Hodges: Stability Control Sites in Two-stranded α-Helical Coiled-coils abs#220 | |
| Peter Hoffmann: Isotope Coded Protein Labelling (ICPL) in combination with Liquid Chromatography MALDI-TOF/TOF mass spectrometry analysis (LC-MALDI) used for the quantification of complex protein mixtures. abs#221 | |
| Hironobu Hojo: Synthesis of glycopeptide dendrimer by the thioester method abs#222 | |
| Jun Ishibashi: N-terminal deamidation of secreted proteins abs#223 | |
| Takashi Iwasaki: Antibacterial and anticancer activity of diastereomeric 9-mer peptides derived from beetle defensins abs#224 | |
| Peter Jackson: Multidimensional Liquid Chromatography of Proteins employing Monolithic WAX and RP Columns abs#225 | |
| Rebecca Jackway: The Formation of the Chemical Messenger Nitric Oxide is Inhibited by the Dahlein 5.6/Calmodulin Complex abs#226 | |
| Bishnu Joshi: Application of Microwave Irradiation to the Synthesis of Pseudopeptides Containing Ester Bond abs#227 | |
| Woo Ram Jung: Proteomic analysis of H19-7 cells induced by tetra-sialogangliosides GQ1b abs#228 | |
| Maria Katsara: T cell receptor altered peptide ligands of Myelin Basic Protein and Proteolipid Protein (Linear and Cyclic) can modulate immune responses in SJL/J mice: Bioactive peptides for Multiple Sclerosis. abs#229 | |
| Koichi Kawasaki: A Tat-related transporter peptide for carrying the adenovirus vector into cells abs#230 | |
| Hong Gi Kim: Decreased Hippocampal Cholinergic Neurostimulating Peptide Precursor Protein associated with Stress Exposure in Rat Brain by Proteomic Analysis abs#231 | |
| Joung Kim: Design and synthesis of pseudopeptide inhibitors for aggregation and fibril formation of Amyloid β protein abs#232 | |
| Hiroyuki Konno: Total Syntheses of Miraziridine A and Its Analogues abs#233 | |
| Chan Lee: New cyclic depsipeptides, enniatin H, I and MK 1688 co-produced with beauvercin by Fusarium oxysporum KFCC11363P abs#234 | |
| KI JUNG LIM: Mechanism of anticancer activity of histonin, a histone H2A-derived peptide abs#235 | |
| Feng Lin: Regioselective disulfide solid phase synthesis of mouse relaxin abs#236 | |
| Ya-Qiu Long: α-Helix Stabilized Peptides via an all Hydrocarbon-staple Conferring an Improved Inhibitory Activity against 3'-Processing of HIV-1 Integrase abs#237 | |
| Nadia Milech: Phylomers: using a new class of natural peptides to target intracellular and extracellular proteins abs#238 | |
| Naoto Minamino: Peptidomic analysis for identification of endogenous peptides and precursor processing profile abs#239 | |
| Hector Montiel: Computer-based screening of functional conformers of proteins abs#240 | |
| Maarja Mäe: Breast tumor homing cell-penetrating peptide chimera targeted delivery in vitro and in vivo. abs#241 | |
| Sarika Namjoshi: Enhanced transdermal delivery of a dipeptide by Dermaportation abs#242 | |
| Kiyoshi Nokihara: Construction of a Mini-library and Structure-functional studies of Maxadilan, a non-mammalian potent vasodilatory peptide, which interacts with the PAC-1 receptor abs#243 | |
| HanBin Oh: ESI-MS approach for screening the Zn(II)-binding peptides abs#244 | |
| MASAKI OKUMURA: Role of pro-leader sequence of de novo designed disulfide hybrid peptides abs#245 | |
| Florian Opperer: N-Methylation of MT-II Backbone Amide Bonds leads to Melanocortin Receptor Selectivity abs#246 | |
| Yoonkyung Park: Trichogin GA IV and its analogues: Mode of Action and Antibiotic Activity against Gram-Positive and MRSA Strains abs#247 | |
| Patrick Perlmutter: Active site specificity of angiotensin converting enzyme 2 using beta-amino acid substrate analogs. abs#248 | |
| Julian Phillips: Liquid Chromatography Optimization for Glycopeptide Analysis by Electron Transfer Dissociation abs#249 | |
| Peter Quaedflieg: Low-cost industrial chemo-enzymatic synthesis of pharmaceutical and nutraceutical oligopeptides abs#250 | |
| Sri Ramarathinam: Mass spectral analysis of β-amino acid containing peptides abs#251 | |
| Denis Scanlon: Microwave Solid Phase Synthesis of Natriuretic Peptide Sequences Derived from the Venom of Exotic Snakes and Lizards abs#253 | |
| Fazel Shabanpoor: Development of a high throughput receptor binding assay using Time-Resolved Fluorescent Europium lanthanide for screening designed insulin-like peptide 3 (INSL3) for their receptor binding affinity. abs#254 | |
| JU RI SHIN: High-level expression of an antimicrobial peptide histonin as a natural form by multimerization and Furin-mediated cleavage abs#255 | |
| Izumi Shiraishi: Design of Histone Deacetylase Inhibitors with Chlamydocin Framework containing Various Imino Acids instead of Proline Residue abs#256 | |
| Jennifer Smith: Investigation into Australian scorpion and centipede venoms abs#257 | |
| Kerstin Steinert: Comparative analysis of membrane glycoproteins from cultured cells abs#258 | |
| Vommina Sureshbabu: The utility of N-Fmoc-Asp/Glu derived 5-oxozolidinones for side chain carboxyl group selective modifications abs#259 | |
| Gilda Tachedjian: Peptides That Modulate HIV-1 Reverse Transcriptase Dimerization and Inhibit Enzyme Function abs#260 | |
| Atsuhiko Taniguchi: Click peptide: Chemical Biology-oriented analogues of Alzheimer's amyloid β peptide 1-42 abs#261 | |
| Philip Thompson: Azabicycloalkane-2-carboxylic acids as scaffolding residues in peptidomimetic design - NK2 antagonists as an example abs#262 | |
| Kellie Tuck: Synthesis of ω-Conotoxin Mimetics in the Development of Novel Analgesics abs#263 | |
| Satoshi Ueno: Mutant of Nematode Cecropin P4 Pro-piece, NP4P, Enhances Activity of Antimicrobial Peptides abs#264 | |
| Karel van wely: Histone binding to the "Death inducer obliterator" protein family abs#265 | |
| Hiroaki Yagi: Substrate Preference of p53-inducible Protein Phosphatase PPM1D abs#266 | |
| Yuri Yamazaki: Tubulin Photoaffinity Labeling Study with Biotin-Tagged Diketopiperazine-Based Anti-Microtubule Agents abs#267 | |
| Taku Yoshiya: Racemization-free segment condensation based on isopeptide method: Toward an efficient preparation of peptides/proteins on solid support abs#268 | |
| Alexander Zamyatnin: Fragmentomics of oligopeptides and proteins abs#269 | |
| suode zhang: Microwave assisted synthesis of N- protected amino acid ester abs#270 | |
| suode zhang: Simultaneous Post-Cysteine(Acm) Group Removal Quenching of Iodination and Isolation of Peptide by One Step Ether Precipitation abs#271 | |
| suode Zhang: Identification of the Receptor Binding Surface of Human Insulin-Like Peptide 3 abs#272 | |
| Lunch for all delegates will be served at the same time in the trade area. | |
| 3:30PM - 5:40PM | Toxins and targets: New Therapeutic and GMO Leads
Chair: Ray Norton and Kyung-Soo Hahm |
| Glenn King: Surprises from spiders: orally active peptide toxins from the inventors of combinatorial peptide chemistry abs#035 | |
| Chunguang Wang: Purification and structural characterization of a D-amino acid containing conopeptide, marmophine, from Conus marmoreus abs#036 | |
| Grzegorz Bulaj: Development of Conus-Derived Therapeutics for Pain via Exogenomics and Peptide Engineering abs#037 | |
| Raymond Norton: Toxin Structures: Through the Looking Glass abs#038 | |
| Richard Lewis: Xen2174: a novel conopeptide NET inhibitor with analgesic potential abs#039 | |
| 3:30PM - 5:30PM | Molecular Interactions - Exploring Affinity & Specificity
Chair: Jackie Wilce and Wally Thomas |
| Stefan Ståhl: Affibody molecules for tumour targeting applications abs#040 | |
| William Gelb: Microcalorimetric Methods for Peptide Studies abs#041 | |
| Gideon Schreiber: New horizons in structure-function studies of protein-protein binding sites using high-throughput SPR abs#042 | |
| Jacqui Matthews: Structural linear binding motifs in LIM-binding proteins abs#043 | |
| Patrick Schaeffer: A New Kind of Protein-DNA Interaction in Termination of DNA Replication abs#044 | |
| Sarah Jones: Mitoparans: mitochondriotoxic cell penetrating peptides and novel inducers of apoptosis abs#045 | |
| 5:30PM - 6:30PM | Happy Hour, Trade & Posters |
Wednesday 24 October
| 8:30AM - 10:30AM | Emerging Technologies for Studying Peptide Structure & Function
Chair: Mibel Aguilar and David Andreu |
| Frances Separovic: Membrane interactions of antimicrobial peptides from Australian tree frogs. abs#046 | |
| Tzong-Hsien (John) Lee: Dynamic geometrical changes of antimicrobial peptides in membrane studied by molecular imaging and optical biosensors abs#047 | |
| Joseph Poduslo: Development of a Peptide-Based Contrast Agent for the Molecular Imaging of Alzheimer's Disease Amyloid Plaques Using High Field Strength Magnetic Resonance abs#048 | |
| Toshimasa Yamazaki: Structure and Function of the N-terminal Domains of SUMO Ligase Siz/PIAS Family abs#049 | |
| Hans-Henrik Kristensen: Plectasin - a new class of peptide antibiotics with potent activities against bacterial infections abs#050 | |
| 10:30AM - 11:30AM | Morning Tea |
| 11:00AM - 1:00PM | New Concepts in Bioactive Peptide Design
Chair: David Craik and Claudio Toniolo |
| Motoyoshi Nomizu: Cell Adhesive Peptides as a Powerful Tool for Cell Engineering abs#051 | |
| Johan Rosengren: Structural insights into the action of relaxin peptide hormones abs#052 | |
| Robert Millar: Ligand-induced-selective-signalling (LiSS) at the Gonadotropin-Releasing-Hormone (GnRH) receptor: delineation of ligand SAR and receptor conformation abs#053 | |
| Morten Meldal: Optical encoding: A general solution to problems in Split/Mix libraries. abs#054 | |
| Phillip Robinson: Peptide inhibitors of dynamin phosphorylation-dependent protein-protein interactions abs#055 | |
| 1:00PM - 6:30PM | Free Afternoon |
Thursday 25 October
| 7:00AM - 8:30AM | Poster Preview |
| Delegates are welcome to browse through the trade hall to observe the posters. | |
| 8:30AM - 10:30AM | Peptidomics: Biomarker analysis and characterization
Chair: Jeff Gorman and Mike Hubbard |
| Hidehito Mukai: Cryptides: Functional Cryptic Peptides Hidden in Protein Structures and Their Novel Signaling Mechanisms abs#056 | |
| Anthony Purcell: Post-Translationally modified peptides - New targets in autoimmune disease? abs#057 | |
| Rudolf Grimm: Latest advancements in HPLC-Chip/MS with applications to proteomics and glycomics research abs#058 | |
| Peter Hoffmann: Super para-magnetic micro particles with different surface modification and their use for the enrichment of peptide classes and their potential as Biomarker Discovery tool. abs#059 | |
| Naoto Minamino: Peptidomic identification of novel neuroendocrine regulatory peptide-1 and -2 abs#060 | |
| 10:30AM - 11:00AM | Morning Tea |
| 11:00AM - 1:00PM | Peptide & Protein Engineering
Chair: Paul Alewood & Bob Hodges |
| Thomas Muir: Semisynthesis of Ubiquitylated Chromatin abs#061 | |
| Takehiko Wada: RNA Recognition and Recognition Control of α-Peptide Ribonucleic Acids Containing Arginine Residue by External Factor abs#062 | |
| Rob Liskamp: Peptides on selectively addressable synthetic scaffolds for mimicry of discontinuous epitopes in proteins: Towards synthetic vaccines and antibodies. abs#063 | |
| Jane Aldrich: Development of centrally acting peptide analogs: structure-transport studies and pharmacological evaluation of analogs of the opioid peptide dynorphin A abs#064 | |
| Yasuhiro Kajihara: Chemical synthesis of glycoproteins having human complex type oligosaccharide abs#065 | |
| 1:00PM - 3:30PM | Poster Session C & Lunch |
| Abu-Baker Abdel-Aal: The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccine abs#301 | |
| Shoji Akita: Development of On-chip Fluorescence Assay for Serine/threonine Kinases abs#302 | |
| Toshinobu Arai: Discovery of novel L-amino acid α-ligases and application to dipeptide synthesis abs#303 | |
| Julie Bergeon: Enhancement of Oral Drug Absorption - Effect of Lipid and Glycoside Conjugation on the Enzymatic Stability and Intestinal Permeability of IM862 abs#304 | |
| Christopher Brown: Constraining peptides in the context of a thioredoxin scaffold abs#305 | |
| Michelle Camerino: New drugs for diabetes: The Design and Molecular Modelling of α -Amylase Peptidomimetics abs#306 | |
| Andrew Coffey: A single source solution to peptide synthesis, analysis and purification abs#307 | |
| Oliver Demmer: Fast and Selective N-Alkylation on Solid Support for SAR Studies and Functionalization of Peptidic CXCR4 Antagonists abs#308 | |
| Thomas Durek: Total chemical synthesis of α-Bungarotoxin analogs as a tool for studying the nicotinic acetylcholine receptor abs#309 | |
| Michael Edmonds: The Effect of Fluorine on the Conformation of β-Amino Acids and β-Peptides abs#310 | |
| Walter Fairlie: Crystal structure of ABT-737 complexed with Bcl-xL: Implications for selectivity of Bcl-2 family antagonists abs#311 | |
| Debby Feytens: New potent Aia-containing SRIF mimetics abs#312 | |
| Yoshio Fujita: Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine abs#313 | |
| Linda Haugaard-Jonsson: Structural Characterization of a H3-INSL5 Relaxin Peptide Chimera abs#314 | |
| Peter Heegaard: A dimerised prion peptide (di PrP 106-126) with enhanced fibrillation activity also show enhanced in vitro caspase induction and in vivo neurotoxicity compared to the monomer peptide (PrP106-126) abs#315 | |
| Jean-Francois Hernandez: Solid phase synthesis of cyclic peptides with a guanidine bridge abs#316 | |
| Jan Hlavácek: Synthesis and characterization of potential inhibitors of dapE and argE enzymes as the new antimicrobial agents abs#317 | |
| Mohammed Hossain: The role of A-chain in the structure and function of human relaxins abs#318 | |