Sponsors of the 8th Australian Peptide Conference, Couran Cove, 2008

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Symposium Proceedings


Peptides - From Discovery to Therapeutics

The 7th in the series of Australian Peptide Conferences was a particularly exciting event as it was held jointly from 21-25 October, 2007, with not only the 4th International Peptide Symposium but also the 2nd Asia-Pacific Peptide Symposium. It was the first time that the International Symposium was held in the southern hemisphere and it was held in the modern city of Cairns, at the northern end of tropical Queensland, a wonderful location for exploring some of Australia's vast array of flora and fauna and natural treasures such as the Great Barrier Reef. More than 400 delegates from all corners of the globe congregated at the superb Cairns Convention Centre to learn of many exciting and rapid advances in peptide research that were provided by the more than 70 oral and 200 poster presentations. These ranged from new synthetic procedures, biology, pharmacology and physiology to the discovery of peptides with novel biological properties, methods for their functional and structural analysis, innovative approaches to elucidate peptide-ligand interactions and new approaches to drug delivery, as well as the emergence of peptide mimetics and peptide-based therapeutics. With the sequencing of the genomes of an increasing number of mammalian species now complete, it is abundantly clear that we are at a particularly rewarding and exciting time as the impacts of genomics, proteomics, and bioinformatics start to drive modern drug discovery.

The collection of fully peer-reviewed articles in this special internet version of the proceedings of the 4th International Peptide Symposium / 7th Australian Peptide Symposium / 2nd Asia-Pacific Peptide Symposium was compiled following our open invitation to all attendees to submit manuscripts. We are delighted to acknowledge an exceptional response, and we believe that the result clearly illustrates both the excellence and diversity of the subject matter that was presented at this exciting joint symposium. We are grateful to not only all authors for their cooperation in ensuring that these proceedings became a reality but also to the many referees, both local and international, who undertook their duties willingly and efficiently. Special thanks must go to Jackie Wilce, the Proceedings editor, whose tireless efforts made this compilation a reality, the outcome of which amply demonstrates the excellence of the 4th International Peptide Symposium / 7th Australian Peptide Symposium / 2nd Asia-Pacific Peptide Symposium. We know that you will find these Proceedings a valuable adjunct to your own research and hope that it will foster new and productive collaborations.

Sincerely,

Ian Smith & John Wade
(Co-Chairmen of the 2007 meeting)


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Any reproduction should only be done with their permission.


Proceedings Topics:

Protein Misfolding & Disease
Peptidomimetics & Drug Design
New Developments in Peptide Drug Delivery
Chemical Peptide Synthesis: Innovations & Applications
Naoko Abe - O-Acyl isopeptide method for peptide synthesis: Application of O-acyl isodipeptide units to the synthesis of bioactive peptides

Toshinobu Arai - Discovery of novel L-amino acid alpha-ligases and application to dipeptide synthesis

Jonathan CollinsSingh - New Developments in Microwave Assisted Solid Phase Peptide Synthesis

Cecile Cros - Designing disaccharide derivatives of Leu-Enkephalin for nasal drug delivery

Oliver Demmer - Fast and Selective N -Alkylation on Solid Support for SAR Studies and Functionalization of Peptidic CXCR4 Antagonists

Xiang Han - Synthesis of RGD Mimetic Peptides with Heterocyclic Residues

Jean-Francois Hernandez - Solid phase synthesis of cyclic peptides with a guanidine bridge

Hironobu Hojo - Synthesis of glycopeptide dendrimer by the thioester method

Bishnu Joshi - Application of rapid Microwave method to the solid phase Synthesis of Pseudopeptides Containing Ester Bond

Toru Kawakami - N to S acyl shift reaction in peptide ligation

Hiroyuki Konno - Total Syntheses of Miraziridine A and Its Analogues

Yuji Nishiuchi - Chloroform-Phenol Mixed Solvent Essential for Segment Condensation Reaction Performed in Solution or on a Solid Support

Nami Ohashi - Chemical Synthesis of a PKC C1b Domain by a Peptide Ligation Method and Expression of the Protein in E. coli and Their Application

Vommina Sureshbabu - Synthesis of tetrazole analogues of amino acids: The Fmoc approach

Vommina Sureshbabu - Total synthesis of Cyclosporin-O

Vommina Sureshbabu - The utility of N -Fmoc-Asp/Glu derived 5-oxozolidinones for side chain carboxyl group selective modifications

Misako Taichi - Suppression of Side Reactions Associated with Use of the N pi-benzyloxymethylhistidine by Performing the HF Reaction in the Presence of Hydroxylamine Derivatives

Taku Yoshiya - Racemization-free segment condensation based on isopeptide method: Toward an efficient preparation of peptides/proteins on solid support

Suode Zhang - Microwave assisted synthesis of N- protected amino acid ester

Peptidomics: Towards Therapeutics
Peptides-to-Clinic
Clinical Proteomics
Toxins and targets: New Therapeutic and GMO Leads
Molecular Interactions - Exploring Affinity & Specificity
Emerging Technologies for Studying Peptide Structure & Function
New Concepts in Bioactive Peptide Design
Peptidomics: Biomarker analysis and characterization
Peptide & Protein Engineering
Peptides as Drugs in Infectious Diseases
Neuropeptides & Pain
Peptide Characterisation


Proceedings