Sponsors of the 8th Australian Peptide Conference, Couran Cove, 2008

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Symposium Proceedings


Peptides - From Discovery to Therapeutics

The 7th in the series of Australian Peptide Conferences was a particularly exciting event as it was held jointly from 21-25 October, 2007, with not only the 4th International Peptide Symposium but also the 2nd Asia-Pacific Peptide Symposium. It was the first time that the International Symposium was held in the southern hemisphere and it was held in the modern city of Cairns, at the northern end of tropical Queensland, a wonderful location for exploring some of Australia's vast array of flora and fauna and natural treasures such as the Great Barrier Reef. More than 400 delegates from all corners of the globe congregated at the superb Cairns Convention Centre to learn of many exciting and rapid advances in peptide research that were provided by the more than 70 oral and 200 poster presentations. These ranged from new synthetic procedures, biology, pharmacology and physiology to the discovery of peptides with novel biological properties, methods for their functional and structural analysis, innovative approaches to elucidate peptide-ligand interactions and new approaches to drug delivery, as well as the emergence of peptide mimetics and peptide-based therapeutics. With the sequencing of the genomes of an increasing number of mammalian species now complete, it is abundantly clear that we are at a particularly rewarding and exciting time as the impacts of genomics, proteomics, and bioinformatics start to drive modern drug discovery.

The collection of fully peer-reviewed articles in this special internet version of the proceedings of the 4th International Peptide Symposium / 7th Australian Peptide Symposium / 2nd Asia-Pacific Peptide Symposium was compiled following our open invitation to all attendees to submit manuscripts. We are delighted to acknowledge an exceptional response, and we believe that the result clearly illustrates both the excellence and diversity of the subject matter that was presented at this exciting joint symposium. We are grateful to not only all authors for their cooperation in ensuring that these proceedings became a reality but also to the many referees, both local and international, who undertook their duties willingly and efficiently. Special thanks must go to Jackie Wilce, the Proceedings editor, whose tireless efforts made this compilation a reality, the outcome of which amply demonstrates the excellence of the 4th International Peptide Symposium / 7th Australian Peptide Symposium / 2nd Asia-Pacific Peptide Symposium. We know that you will find these Proceedings a valuable adjunct to your own research and hope that it will foster new and productive collaborations.

Sincerely,

Ian Smith & John Wade
(Co-Chairmen of the 2007 meeting)


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Proceedings Topics:

Protein Misfolding & Disease
Peptidomimetics & Drug Design
New Developments in Peptide Drug Delivery
Chemical Peptide Synthesis: Innovations & Applications
Peptidomics: Towards Therapeutics
Peptides-to-Clinic
Clinical Proteomics
Toxins and targets: New Therapeutic and GMO Leads
Molecular Interactions - Exploring Affinity & Specificity
Emerging Technologies for Studying Peptide Structure & Function
New Concepts in Bioactive Peptide Design
Abu-Baker Abdel-Aal - The importance of epitope and lipid orientation in the design of synthetic self-adjuvanting group A streptococcal (GAS) vaccine

Yoshio Fujita - Development of a Multivalent Heteroepitopic Group A Streptococcus Vaccine

Robert Hodges - Stability Control Sites in Two-stranded alpha-Helical Coiled-Coils

John Howl - Identification and biological applications of rhegnylogically-organized cell penetrating peptides

Sarah Jones - Mitoparans: mitochondriotoxic cell penetrating peptides and novel inducers of apoptosis

Rasmus Karstad - The use of Arginine Analogs in the Preparation of Short Cationic Antimicrobial Peptides

Maria Katsara - T cell receptor altered peptide ligands of Myelin Basic Protein and Proteolipid Protein (Linear and Cyclic) can modulate immune responses in SJL/J mice: Bioactive peptides for Multiple Sclerosis.

Sung Kim - Comparative structure-activity relationships of indolicidin and its analogues

Ya-Qiu Long - alpha-Helix Stabilized Peptides via an all Hydrocarbon-staple Conferring an Improved Inhibitory Activity against 3'-Processing of HIV-1 Integrase

Maria Luisa Mangoni - LPS (Endotoxin) is a Key Molecule in the Synergistic Effect of Temporins on Gram-Negative Bacteria

Kiyoshi Nokihara - Construction of a Mini-library and Structure-functional studies of Maxadilan, a non-mammalian potent vasodilatory peptide, which interacts with the PAC-1 receptor

Motoyoshi Nomizu - Cell Adhesive Peptides as a Powerful Tool for Cell Engineering

Johan Rosengren - Structural insights into the action of relaxin peptide hormones

Fazel Shabanpoor - Design, Sythesis and pharmacological evaluation of novel INSL3 antagonists

Izumi Shiraishi - Design of Histone Deacetylase Inhibitors with Chlamydocin Framework containing Various Imino Acids instead of Proline Residue

Masakazu Tanaka - Molecular Design for Chiral Cyclic alpha,alpha-Disubstituted Amino Acids and Conformational Study of Their Peptides

Atsuhiko Taniguchi - Click peptide: Chemical Biology-oriented analogues of Alzheimer's amyloid beta peptide 1-42

Claudio Toniolo - Does C alpha-methyl proline prefer the helical or the semi-extended conformation? A Janus-headed, C alpha-tetrasubstituted alpha-amino acid

Peptidomics: Biomarker analysis and characterization
Peptide & Protein Engineering
Peptides as Drugs in Infectious Diseases
Neuropeptides & Pain
Peptide Characterisation


Proceedings